Laboratory for investigation of natural resources of pharmacologically and biologically active compounds (LAFIB) was established in 2012 at the Department of Chemistry, Biochemistry and Environmental Protection, Faculty of Sciences, University of Novi Sad, Serbia. LAFIB is the result of long-standing experience in the research of bioactive molecules from natural sources and their possible applications in the pharmaceutical, food and cosmetic industries. Thanks to successful participation in many national and international research projects, LAFIB obtained the state-of-the-art laboratory equipment which is the basis for conducting the high quality scientific research. LAFIB young research team, coordinated by Prof. Dr. Neda Mimica-Dukić, are well recognized for scientific achievements as verified by a considerable number of publications in high-impact peer-reviewed scientific journals. LAFIB is acknowledged for providing laboratory services and consulting in the relevant fields of expertise to members of the academic community, SMEs and individual producers.
LAFIB’s main research directions are:
· Isolation and chemical characterization of biomolecules from medicinal and edible plants, spices, plant extracts, commercial phytopreparations, essential oils and other products;
· Determination of biological and pharmacological activities (antioxidant, anti-inflammatory, antiproliferative) of biomolecules from medicinal and edible plants, spices, plant extracts, commercial phytopreparations, essential oils and other products.
Research conducted at LAFIB is of both fundamental and applied nature. Fundamental research includes mechanistic studies of the role of plant biomolecules in complex biochemical pathways in animal cells, such as oxidative stress defence, inflammation, cancerogenesis. Under this framework, a special attention is devoted to examination of the structure-activity relationship. Also, fundamental research is related to plant chemotaxonomy and the influence of various ecological factors on plant chemical
composition. Applied research is focused on the possible utilization of plant biomolecules, plant extracts and phytopreparations in various industries.
LAFIB offers a wide range of expert laboratory services and consulting to SMEs and individual subjects. (http://www.dh.uns.ac.rs/lafib/english/lafib_pricelist.pdf). We organize trainings, targeted thematic meetings, seminars and workshops for SMEs dealing with production and utilization of medicinal and edible plants, spices and phytopreparations.
We are open to networking, participation in projects, and establishing new collaborations both at the national and international level. LAFIB’s mission is to constantly build its capacities and engage in responsible research for the benefit of science and society! For additional information please contact us (http://www.dh.uns.ac.rs/lafib/english/contact.php).
| Name | Host institution | |
|---|---|---|
Mimica-Dukić Neda |
neda.mimica-dukic@dh.uns.ac.rs | Faculty of Science in Novi Sad |
| Beara Ivana | ivana.beara@dh.uns.ac.rs | Faculty of Science in Novi Sad |
| Bekvalac Kristina | kristina.bekvalac@dh.uns.ac.rs | Faculty of Science in Novi Sad |
| Francišković Marina | marina.franciskovic@dh.uns.ac.r | Faculty of Science in Novi Sad |
| Lesjak Marija | marija.lesjak@dh.uns.ac.rs | Faculty of Science in Novi Sad |
| Orčić Dejan | dejan.orcic@dh.uns.ac.rs | Faculty of Science in Novi Sad |
| Šibul Filip | filip.sibul@dh.uns.ac.rs | Faculty of Science in Novi Sad |
| Simin Nataša | natasa.simin@dh.uns.ac.rs | Faculty of Science in Novi Sad |
| Svirčev Emilija | emilija.svircev@dh.uns.ac.rs | Faculty of Science in Novi Sad |
LAFIB is mainly research oriented. Within the past five years, numerous papers were published in highly ranked international scientific journals. LAFIB participated in the development, optimization and quality control of several herbal formulations.
• Lesjak, M., Beara, I., Orčić, D., Ristić, J., Anačkov, G., Božin, B., Mimica-Dukić, N. (2013): Chemical characterisation and biological effects of Juniperus foetidissima Willd. 1806. LWT-Food Science and Technology, 53:530-539.
• Beara, I., Lesjak, M., Orčić, D., Simin, N., Četojević-Simin, D., Božin, B., Mimica-Dukić, N. (2012): Comparative analysis of phenolic profile, antioxidant activity and cytotoxic activity of two closely related species: Plantago altissima L. and Plantago lanceolata L. LWT-Food Science and Technology. 47:64-70.
• Lesjak, M., Beara, I., Orčić, D., Anačkov, G., Balog, K., Francišković, M., Mimica-Dukić, N. (2011): Juniperus sibirica Burgsdorf. as a novel source of antioxidant and anti-inflammatory agents. Food Chemistry. 124:850-856.
• Orčić, D., Mimica-Dukić, N., Francišković, M., Petrović, S., Jovin, E. (2011): Antioxidant activity relationship of phenolic compounds in Hypericum perforatum L. Chemistry Central Journal. 5:34-41.
• Mimica-Dukić, N., Bugarin, D., Grbović, S., Mitić-Ćulafić, D., Vuković-Gačić, B., Orčić D., Jovin, E., Couladis, M. (2010): Essential Oil of Myrtus communis L. as a Potential Antioxidant and Antimutagenic Agents. Molecules. 5:2759-2770.